zinc finger造句

• Hormones promote expression ofhzfl , & hyacinthus zinc finger gene , during 24 hours cultured
  外源激素在短时间内诱导锌指蛋白基因hzf1的高水平表达。
• In this study , we have identified four novel human krlipple - like zinc finger genes named znf325 , znf359 , zfp28 and znf323
  本实验中，我们克隆了四个人类cys2 his2型锌指蛋白基因znf325 ， znf359 ， zfp28和znf323 。
• Taken together , these results indicate that these genes are members of zinc finger transcription factor family and may be involved in the development of multiple embryonic organs
  综合这些基因的结构和表达特征，我们可以初步得出一个结论：它们编码的是参与多种人类胚胎器官发生的锌指转录调控因子。
• The complete human znf323 cdna sequence is 3179bp and contains a 1221 - bp open reading frame ( orf ) that encodes a 407 amino acid protein with a scan domain and 6 zinc finger c2i12 motifs
  Znf323长3179个碱基，含有一个长为1221个碱基的开放阅读框，编码一个长为407个氨基酸的蛋白质，它包含一个scan框和6个c2h2型锌指。
• The zfp28 cdna sequence is 4104 bp and contains a 2076 bp orf that encodes and 868 amino acids protein with an n - terminal signal peptide , two krab domain , and 14 c - termianal c2h2 zinc finger motifs
  Zfp28基因长4076个碱基，含8个外显子，在基因组dna上长18kb 。它编码的蛋白质全长868个氨基酸，含1个信号肽， 2个krab框和14个c2h2型的锌指。
• The cys2 / his2 type zinc finger genes are the single largest class of transcription factors in the human genome and many numbers of these krtlpple - like zinc finger genes have been found to be involved in cardiac development or cardiovascular diseases
  Cys2 his2型锌指蛋白基因是一类很大的转录调控因子家族基因，已发现很多cys2 his2型锌指蛋白参与了心脏发育和心血管疾病。
• The complete human znf359 cdna sequence is 3270 bp and contains a 1932 bp open reading frame ( orf ) that encodes a 643 amino acid protein with an n - terminal krab domain and 16 c - terminus zinc finger c2h2 motifs
  Znf359基因长3271个碱基，含6个外显子，在基因组dna上长18kb 。它编码的蛋白质全长643个氨基酸，含一个krab框， 16个c2h2型的锌指，在两者之间还有一个典型的中间重复序列。
• The znf360 mrnn a is 4031 bp , which spans 17 . 3 kb and is organized into eight exons . the preduced protein coded by znf360 gene contains 977 amino acids , including a krab motif , a scan motif , two sant motifs and ten krtlpple type zinc fingers
  Znf360基因全长4031个碱基，含8个外显子，在基因组dna上长17 . 3kb ，其编码蛋白质全长977个氨基酸，含一个krab框、一个scan框、两个sant框和10个kr pple型的锌指。
• The former four genes were belonged to krupple - type zinc finger family and irxl was belonged to iroquois homeobox family . both of the families are transcription factors . it was shown that the two family proteins are involved in the cardiogenesis process or cardiac disease
  前面4个基因属于c2h2 -型锌指蛋白家族， irx1属irx蛋白家族，它们都是转录因子，研究表明这两个家族蛋白都参与心脏的发育或疾病发生过程。
• So it is response to the exogeneous hoemones at an early stage . hormones are essential for maintaining the expression of hrz , a ring zinc finger gene . hrz expresses in the explants cultured with hormones for 10 days and the level of expression is declined at day 15
  因此， hzfj在外源激素的作用下，只在较短的时间内表达水平提高，表明该基因是对外源激素响应的早期基回c环状锌指蛋白基因hrz在未培养的外植体中表达。
• The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation , such as zinc finger 198 , 263 , 14 , 224 , zf6 , novel protein similar to transcriptional represser ctcf , and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction , cell - cycle control , chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions
  鉴定出的蛋白包括多个与转录调控相关的锌指蛋白，如锌指蛋白198 、 263 、 14 、 224 、 zf6 、转录抑制因子ctcf样蛋白、幻肚pple样锌指蛋白等:两个含金属蛋白酶结构域和整合素结合结构域的家族成员adam28和adam17 ;两个整合素家族成员pz整合素和含十个egf样结构域的整合素( tied ) ;与细胞信号转导通路有关的蛋白;与细胞周期调控有关的蛋白;与染色体重塑和基因转录抑制有关的蛋白;细胞骨架蛋白以及其他功能未明的蛋白等。
• The complete human znf325 cdna sequence is 2697bp and contains a 1389 - bp open reading frame ( orf ) that encodes a 462 amino acid protein with 15 zinc finger c2h2 motifs . the complete human znf359 cdna sequence is 3270bp and contains a 1932 - bp open read ing frame ( orf ) that encodes a 643 amino acid protein with an n - terminal krab domain and 16 c - terminus zinc finger c2h2 motifs . the zfp28 cdna sequence is 4104bp and contains a 2076 - bp open reading frame ( orf ) that encodes an 868 amino acid protein with an n - terminal signal peptide , two krab domains and 14 c - terminal c2h2 zinc finger motifs
  Znf325长2697个碱基，含有一个长为1389个碱基的开放阅读框，编码一个长为462个氨基酸的蛋白质，它包含15个c2h2型锌指结构； znf359长3270个碱基，含有一个长为1932个碱基的开放阅读框，编码一个长为643个氨基酸的蛋白质，它包含一个n -端krab结构域和16个c -端c2h2型锌指结构； zfp28长4104个碱基，含有一个长为2076个碱基的开放阅读框，编码一个长为868个氨基酸的蛋白质，它包含一个n -端信号肽，两个krab结构域和14个c -端c2h2型锌指结构。
• The krupple type zinc finger motif found in many transcription factors is thought to be important for nucleic acid binding and / or dimerization . here we have identified and characterized two novel zinc finger genes named znf323 and znf360 using degenerate primers from an early human embryo heart cdna library
  本文利用kr ppel型( cys _ 2 his _ 2型)锌指基因顺序上的保守特征，设计简并引物从人类早期胚胎cdna文库中初步筛选克隆出四个kr pple型锌指蛋白新基因，经国际基因命名委员会批准命名为znf323 、 znf360 、 znf359和zfp28 。